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The completion of GSH synthesis is catalyzed by glutathione synthetase (GS), in a reaction in which -glutamyl-cysteine is covalently linked to glycine ( Figure 1 )
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Werner syndrome (WS), which is distinguished by severe metabolic dysfunction, dyslipidemia, early atherosclerosis, and insulin resistance diabetes, is thought to most closely mimic normal aging
Ensuring careful management of medication schedules and consulting a doctor before starting new medications is crucial
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